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Eye drops: how to use them correctly and what to check before opening a bottle

Before putting drops in your eye, know three things: what the product is supposed to do, which eye it is intended for, and how long it can be used after opening. A bottle left from previous treatment is not necessarily suitable for a new symptom, and even nonprescription drops must be used according to the leaflet. The difference between helpful treatment and incorrect use sometimes begins with reading the label.

Adi Way Editorial TeamPublished:

Illustration: a closed eye-drop bottle beside its packaging and a folded hand towel on a clean surface
Illustrative image.

The following guide explains how to distinguish treatment purposes, keep the bottle clean, and organize several types of drops. It does not replace diagnosis or personal instructions: significant pain or a change in vision requires examination, not an experiment with another product.

The same small bottle, different treatment purposes

Lubricating drops, also called artificial tears, are a common treatment for mild dry eyes. According to the U.S. National Eye Institute (NEI), dry eye treatment may also include prescription medications and changes in habits, depending on the cause and severity. Relief after applying drops therefore does not, by itself, explain the source of the complaint.

Antibiotic drops are intended for certain bacterial infections. The British National Health Service, the NHS, explains in its conjunctivitis guidance that antibiotics do not help when the cause is a virus or allergy. A red eye is not a diagnosis, and discharge or itching is not enough to select treatment yourself.

Steroid drops reduce inflammation in conditions for which they have been prescribed. They require attention to treatment duration and follow-up. The NHS notes that treatment with dexamethasone eye drops may require checks for intraocular pressure and signs of infection; sometimes the doctor instructs a gradual dose reduction. Do not restart an old bottle of steroids, extend treatment, or change the tapering plan solely because you feel better.

Before every use: identify, check, read

Read the product name and instructions, even if the bottle is familiar. Check that the drops are intended for the eyes, the prescribed quantity, and whether treatment is for the right eye, left eye, or both. Cap color can help you find your way around, but does not replace identifying the medication.

Moorfields Eye Hospital recommends checking both the printed expiration date and the permitted period of use after opening. These are two different details: a distant expiration date does not guarantee that an open bottle is still suitable for use. The period after opening varies between products, so no single rule fits all drops.

Writing the opening date on the bottle or packaging prevents guesswork later. Store according to the product instructions; refrigeration is not automatically required. Do not share drops with another person. If you do not know when a bottle was opened, or a new product's seal is damaged, contact a pharmacist before using it.

How to apply drops without touching the eye

NEI guidance emphasizes washing your hands and keeping the bottle tip from touching your eye, eyelid, or fingers. The U.S. Food and Drug Administration (FDA) explains that eye products must be sterile to reduce infection risk. Even a surface that looks clean is not a place to rest the tip.

  1. Wash your hands with soap and water. Shake the product only if its instructions require it.
  2. Tilt your head back and gently pull down your lower eyelid to create a small pocket.
  3. Hold the tip above the pocket without touching the eye, eyelashes, or skin, and apply the prescribed number of drops.
  4. Close your eye gently. According to NEI guidance, light pressure at the inner corner, near the nose, for at least a minute helps reduce drainage into the nose. Do not press on the eyeball.
  5. Close the bottle after use and store it according to the leaflet.

If aiming or squeezing the bottle is difficult, ask a pharmacist or clinic staff to demonstrate a suitable aid. This is a technical difficulty worth resolving, especially for ongoing treatment.

Several types of drops need a clear order

According to NEI instructions, wait at least five minutes between different types of drops unless you have received different specific instructions. Do not add more drops than prescribed in an attempt to strengthen the treatment.

Make a short list on your phone: product name, eye being treated, application times, and the end or follow-up date. For example, if you have morning drops and additional evening drops, writing their full names is more useful than calling one "the white bottle." This helps organize the instructions you received; it is not a dosage recommendation.

Contact lens wearers need to establish whether the drops are suitable for use with lenses, and if removal is required, when lenses may be reinserted. Do not copy the waiting time from another product. If you miss a dose, check the product instructions or ask a pharmacist before making up for it.

When to seek an examination instead of changing drops

According to NHS guidance on red eyes, a red eye with a change in vision, pain when looking at light, or a severe headache and nausea requires immediate medical care. Sudden loss of vision also requires urgent assessment. In Israel, go to an eye emergency department if available, or an emergency department, rather than waiting for a routine appointment. Do not drive if your vision is affected.

A red eye in a contact lens wearer requires urgent same-day examination because of the possibility of infection. Remove your lenses and do not reinsert them until instructed. If redness comes with significant pain or impaired vision, seek care immediately. Drops left at home are no reason to delay examination.

Brief discomfort may occur with certain products, but do not assume persistent pain or worsening blur is a normal reaction. Contact a medical professional and bring the bottle or a clear photograph of the label. This allows identification of what was given and when, without relying on memory.

What to clarify before leaving the clinic

Ask for clear answers to four questions: what the drops are for, how long treatment is intended to last, whether follow-up is required, and what to do if an unexpected reaction occurs. If you take other medications or use other drops, show a list of them.

For additional background, you can also visit Professor Michael Mimouni's website. Online information can help prepare questions, but the instructions for your product and condition are the basis for its use.

The information in this article is general and is not a substitute for an examination, diagnosis, or personal medical instructions. If you have any doubts about a particular product, contact a doctor or pharmacist with its name and leaflet.

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